Adult-onset Still disease
MONDO:0019355A rare inflammatory multisystem disorder characterized clinically by fever of unknown origin, arthralgia or arthritis, hyperleucocytosis, and typical skin rash.
Also known as: AOSD, Adult-Onset Still's Disease, Wissler-Fanconi syndrome, adult-onset Still disease, adult-onset Still's disease, Still's disease adult onset, adult Still's disease
46 clinical trials for this condition and its sub-types, 12 tagged with Adult-onset Still disease itself.
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New hope for rare inflammatory disease? sirolimus tested in stubborn cases
Disease control OngoingThis study tests whether sirolimus, a drug that calms the immune system, can help people with Adult-Onset Still's disease whose symptoms don't improve with standard steroids. Three adults with this rare inflammatory condition will take sirolimus pills for 12 weeks while doctors m…
Sponsor: Ruijin Hospital • Aim: Disease control
Last updated Aug 20, 2026 00:00 UTC
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Could a daily injection tame two rare inflammatory diseases?
Disease control CancelledThis study tests the drug anakinra in Chinese patients with two related inflammatory conditions: Systemic Juvenile Idiopathic Arthritis (SJIA) in children and Adult-Onset Still's Disease (AOSD) in adults. Participants receive a daily injection under the skin for 48 weeks. The goa…
Phase 4 • Sponsor: Swedish Orphan Biovitrum • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC