Acute myeloid leukemia with multilineage dysplasia
MONDO:0019456An acute myeloid leukemia arising de novo and not as a result of treatment. It is characterized by the presence of myelodysplastic features in at least 50% of the cells of at least two hematopoietic cell lines. Patients often present with severe cytopenia.
Also known as: AML with multilineage dysplasia, AML with myelodysplasia-related features, De novo acute myeloid leukaemia with multilineage dysplasia, De novo acute myeloid leukemia with multilineage dysplasia, acute myeloid leukaemia with myelodysplasia-related features, acute myeloid leukemia with myelodysplasia-related features
3123 clinical trials for this condition and its sub-types, 34 tagged with Acute myeloid leukemia with multilineage dysplasia itself.
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Experimental combo for resistant leukemia shows early promise but trial halted
Disease control Stopped earlyThis pilot study tested a new drug called sEphB4-HSA combined with standard chemotherapy (azacitidine or decitabine) in 7 patients with myelodysplastic syndrome, chronic myelomonocytic leukemia, or acute myeloid leukemia that had returned or not responded to prior treatment. The …
Phase 2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Promising combo for tough leukemias hits snag: trial ends early
Disease control Stopped earlyThis phase II trial tested a combination of two drugs, venetoclax and decitabine, in 235 patients with certain blood cancers like acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS) that had come back or not responded to treatment, as well as in older patien…
Phase 2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC