Acute myeloblastic leukemia without maturation
MONDO:0005224An acute myeloid leukemia (AML) characterized by blasts without evidence of maturation to more mature neutrophils. (WHO, 2001)
Also known as: AML M1, AML without maturation, FAB M1, M1 acute granulocytic leukaemia, M1 acute granulocytic leukaemia without maturation, M1 acute granulocytic leukemia, M1 acute granulocytic leukemia without maturation, M1 acute myeloblastic leukaemia
3091 clinical trials for this condition and its sub-types, 4 tagged with Acute myeloblastic leukemia without maturation itself.
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New combo therapy shows promise for older leukemia patients
Disease control OngoingThis study tested a combination of two drugs, azacitidine and gemtuzumab ozogamicin, in 133 older adults (age 60+) with untreated acute myeloid leukemia. The goal was to see how well the treatment could put the cancer into remission and improve survival. The approach uses chemoth…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Can a 'Priming' drug boost chemo for tough leukemia?
Disease control OngoingThis phase 2 trial tests whether adding the drug decitabine to standard chemotherapy improves remission rates in adults with acute myeloid leukemia (AML) who have less favorable genetic risk. Decitabine is given before chemo to try to make cancer cells more sensitive. About 178 p…
Phase 2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC