Acute myeloblastic leukemia with maturation
MONDO:0020320An acute myeloid leukemia (AML) characterized by blasts with evidence of maturation to more mature neutrophils. (WHO, 2001)
Also known as: AML M2, AML with maturation, FAB M2, M2 acute granulocytic leukaemia, M2 acute granulocytic leukemia, M2 acute myeloblastic leukaemia, M2 acute myeloblastic leukaemia with maturation, M2 acute myeloblastic leukemia
3115 clinical trials for this condition and its sub-types, 26 tagged with Acute myeloblastic leukemia with maturation itself.
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New hope for AML patients: experimental drug IPN60340 enters key trial
Disease control Not yet recruitingThis study tests whether adding the experimental drug IPN60340 to standard medicines (azacitidine and venetoclax) helps more people with newly diagnosed acute myeloid leukemia (AML) achieve complete remission. About 450 adults who cannot have intensive chemotherapy will take part…
Phase 2/3 • Sponsor: Ipsen • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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New drug cocktail aims to wipe out lingering leukemia
Disease control Not yet recruitingThis study tests whether combining two oral drugs, sorafenib and venetoclax, can eliminate leftover leukemia cells in people with acute myeloid leukemia (AML) who still have measurable residual disease (MRD) after initial treatment. About 87 participants will receive the drugs fo…
Phase 2/3 • Sponsor: Nanfang Hospital, Southern Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:01 UTC
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New blood test could personalize AML treatment
Diagnosis Not yet recruitingThis study tests a new blood test (5hmC) to see if it can help doctors choose between two standard treatments for acute myeloid leukemia (AML): a milder drug (hypomethylating agent) or strong chemotherapy. About 112 newly diagnosed adults will have their blood tested after initia…
Phase 2 • Sponsor: The Methodist Hospital Research Institute • Aim: Diagnosis
Last updated Jun 27, 2026 09:11 UTC
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Chemotherapy at home for leukemia: a feasibility test
Knowledge-focused Not yet recruitingThis study explores whether patients with acute myeloid leukemia can receive intravenous cytarabine chemotherapy at home instead of in the hospital. Researchers will track how many patients complete the planned home treatment, how often doses are given at home versus the hospital…
Sponsor: Zealand University Hospital • Aim: Knowledge-focused
Last updated Sep 05, 2026 00:00 UTC