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Up to: Pseudohypoparathyroidism · Disorder of GNAS inactivation

Pseudohypoparathyroidism type 1B

Pseudohypoparathyroidism type 1B (PHP-1b) is a type of pseudohypoparathyroidism (PHP) characterized by localized resistance to parathyroid hormone (PTH) mainly in the renal tissues which manifests with hypocalcemia, hyperphosphatemia and elevated PTH levels. About 60-70% of patients also present with elevated TSH levels due to TSH resistance.

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This condition has no sub-types.