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Up to: X-linked disease · Hyper-IgM syndrome
Hyper-IgM syndrome type 1
The X-linked variant of the Hyper-IgM syndrome. The affected individuals are virtually always male, because males only have one X chromosome, received from their mothers. Their mothers are not symptomatic, even though they are carriers of the allele, because the trait is recessive. Male offspring of these women have a 50% chance of inheriting their mother's mutant allele.
This condition has no sub-types.