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Up to: Autosomal dominant complex spastic paraplegia
Spastic paraplegia-precocious puberty syndrome
Spastic paraplegia-precocious puberty syndrome is characterized by precocious puberty (due to Leydig cell hyperplasia), progressive spastic paraplegia and intellectual deficit. It has been described in two brothers. The fact that other family members displayed brisk reflexes and dysarthria suggested autosomal dominant inheritance with variable expression.
This condition has no sub-types.