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Up to: Disorder of development or morphogenesis · Cardiogenetic disease · Aortic valve disorder

Familial bicuspid aortic valve

A rare, genetic, aortic malformation defined as a presence of abnormal two-leaflet aortic valve in at least 2 first-degree relatives. It is frequently asymptomatic or may be associated with progressive aortic valve disease (aortic regurgitation and/or aortic stenosis, typically due to valve calcification) and a concomitant aortopathy (i.e. aortic dilation, aortic aneurysm and/or dissection).

6 trials tagged with this condition →