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Prion disease

A transmissible disease that is caused by a protein that is able to induce abnormal folding of normal cellular proteins, leading to characteristic spongiform brain changes, which are associated with neuronal loss without an inflammatory response. Such disorders have typically long incubation periods, but are then generally rapidly progressive and are uniformly fatal.

5 trials tagged with this condition →

Creutzfeldt Jacob disease 4 trials · 7 incl. sub-types Sub-types →
Fatal familial insomnia 4 trials
Gerstmann-Straussler-Scheinker syndrome 1 trial
Huntington disease-like 1 0 trials
PrP systemic amyloidosis 0 trials
Familial Alzheimer-like prion disease 0 trials
Kuru 0 trials
Scrapie 0 trials
Spongiform encephalopathy with neuropsychiatric features 0 trials
Sporadic fatal insomnia 0 trials