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Up to: B-cell neoplasm
Neoplasm of mature B-cells
A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001).
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Plasma cell neoplasm 108 trials · 1,151 incl. sub-types Sub-types →
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Diffuse large B-cell lymphoma 633 trials · 755 incl. sub-types Sub-types →
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Follicular lymphoma 590 trials
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B-cell chronic lymphocytic leukemia 509 trials · 538 incl. sub-types Sub-types →
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Burkitt lymphoma 221 trials Sub-types →
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Primary central nervous system lymphoma 92 trials · 103 incl. sub-types Sub-types →
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MALT lymphoma 30 trials · 31 incl. sub-types Sub-types →
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B-cell prolymphocytic leukemia 7 trials