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Up to: Autosomal recessive disease · Inherited lipid metabolism disorder · Developmental anomaly of metabolic origin · Disorder of GPI anchor biosynthesis · Multiple congenital anomalies/dysmorphic syndrome-intellectual disability

Glycosylphosphatidylinositol biosynthesis defect 15

A rare, genetic, syndromic intellectual disability characterized by global developmental delay, early-onset seizures, cerebellar atrophy, osteopenia, nystagmus and dysmorphic facial features, including bitemporal narrowing, prominent forehead, anteverted nares. Dysarthria, dysmetria, ataxic gait, spasticity and dysmorphic features have also been associated.

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