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Up to: Gastrointestinal defect and immunodeficiency syndrome · PI4KA-related disorder

Gastrointestinal defects and immunodeficiency syndrome 2

A severe autosomal recessive developmental disorder characterized by multiple intestinal atresia apparent soon after birth. Affected infants have a distended abdomen and do not pass meconium. There is some evidence of inflammatory bowel disease. Death occurs in the first weeks of life. Some patients may also have immunodeficiency.

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