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Up to: Syndromic disease · Ciliopathy · Hereditary lethal multiple congenital anomalies/dysmorphic syndrome

Meckel syndrome

A rare, lethal, genetic, multiple congenital anomaly disorder characterized by the triad of brain malformation mainly occipital encephalocele, large polycystic kidneys, and polydactyly as well as associated abnormalities that may include cleft lip/palate, cardiac and genital anomalies, central nervous system (CNS) malformations, liver fibrosis, and bone dysplasia.

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