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Up to: Hereditary neurological disease · Hereditary neoplastic syndrome · Autosomal dominant disease
Li-Fraumeni syndrome
An autosomal dominant cancer predisposition disorder caused by pathogenic variants in the TP53 gene, characterized by an increased risk of a wide range of cancers, including but not limited to breast cancer, soft tissue sarcomas, osteosarcomas, brain tumors, adrenocortical carcinoma and leukemias.
This condition has no sub-types.