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Up to: Inborn errors of metabolism · Developmental anomaly of metabolic origin

Hypophosphatasia

Hypophosphatasia (HPP) is a rare heritable metabolic disorder characterized by defective mineralization of bone and/or teeth in the presence of reduced activity of unfractionated serum alkaline phosphatase (ALP). The clinical spectrum is extremely wide, from stillbirth at one end to fractures of the lower extremities in adulthood, at the other, or even no bone manifestations (odontohypophosphatasia).

13 trials tagged with this condition →

ALPL-related autosomal dominant hypophosphatasia 0 trials Sub-types →
ALPL-related autosomal recessive hypophosphatasia 0 trials Sub-types →
Adult hypophosphatasia 0 trials
Childhood hypophosphatasia 0 trials
Infantile hypophosphatasia 0 trials
Moderate hypophosphatasia 0 trials
Odontohypophosphatasia 0 trials
Prenatal benign hypophosphatasia 0 trials