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T-B- severe combined immunodeficiency

T-B- severe combined immunodeficiency (SCID) is a group of rare monogenic primary immunodeficiency disorders characterized by a lack of functional peripheral T and B lymphocytes, resulting in recurrent early-onset severe respiratory viral, bacterial or fungal infections, diarrhea and failure to thrive. Hypersensitivity to ionizing radiation is a characteristic feature of some of its sub-types.

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Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-negative, due to adenosine deaminase deficiency 6 trials
Omenn syndrome 4 trials
Severe combined immunodeficiency due to DCLRE1C deficiency 3 trials
Severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive 2 trials
DNA ligase IV deficiency 1 trial
Reticular dysgenesis 1 trial Sub-types →
Cernunnos-XLF deficiency 0 trials
Combined immunodeficiency due to partial RAG1 deficiency 0 trials
Combined immunodeficiency with skin granulomas 0 trials
Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia 0 trials
Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia 0 trials
Neutrophil immunodeficiency syndrome 0 trials
Reticular dysgenesis-like severe combined immunodeficiency 0 trials
Severe combined immunodeficiency due to DNA-PKcs deficiency 0 trials
Severe combined immunodeficiency due to LCK deficiency 0 trials
Short-limb skeletal dysplasia with severe combined immunodeficiency 0 trials