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Up to: Multiple congenital anomalies/dysmorphic syndrome-intellectual disability · Overgrowth syndrome · Partial duplication of the short arm of chromosome 11

11p15.4 microduplication syndrome

11p15.4 microduplication syndrome is a rare partial autosomal trisomy/tetrasomy characterized by obesity, global developmental delay and intellectual disability, facial dysmorphism (synophrys, high-arched eyebrows, large posteriorly rotated ears, upturned nose, long smooth philtrum, overbite and high palate), large hands and limb hypotonia. Additional features include seizures and behavioral abnormalities.

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