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Up to: Congenital disorder of glycosylation type I · Disorder of protein N-glycosylation

ALG2-congenital disorder of glycosylation

A form of congenital disorders of N-linked glycosylation characterized by iris coloboma, cataract, infantile spasms, developmental delay and abnormal coagulation factors. The disease is caused by loss-of-function mutations in the gene ALG2 (9q31.1). Transmission is autosomal recessive.

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