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Up to: Hereditary ataxia · Mitochondrial oxidative phosphorylation disorder · Hereditary spastic paraplegia

Hereditary spastic paraplegia 7

Autosomal recessive spastic paraplegia type 7 is a form of hereditary spastic paraplegia characterized by an onset usually in adulthood (but ranging from 10-72 years) of progressive bilateral lower limb weakness and spasticity, sphincter dysfunction, decreased vibratory sense at the ankles and with additional manifestations including optical neuropathy, nystagmus, strabismus, decreased hearing, scoliosis, pes cavus, motor and sensory neuropathy, amyotrophy, blepharoptosis and ophthalmoplegia.

1 trial tagged with this condition →

This condition has no sub-types.