New drug combo tested for Tough-to-Treat digestive cancers

NCT ID NCT03929666

Summary

This study tested whether adding an experimental drug called ZW25 to standard chemotherapy could help control advanced stomach, bile duct, and colorectal cancers that have a specific marker called HER2. It involved 74 patients with these cancers that could not be removed by surgery. The research first checked the safety of the combination, then measured how well tumors responded to the treatment.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • CECIM Biocinetic

    Santiago, 8320000, Chile

  • Centro Internacional de Estudios Clínicos

    Santiago, 8420383, Chile

  • Centro de Investigacion Clinica SAGA

    Santiago, 7500653, Chile

  • Fox Chase Cancer Center

    Philadelphia, Pennsylvania, 19111, United States

  • H. Lee Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • Hoag Memorial Hospital Presbyterian

    Newport Beach, California, 92663, United States

  • Icegclinic Research & Care

    Santiago, 8241479, Chile

  • Korea University Anam Hospital

    Seoul, 02841, South Korea

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Nebraska Methodist Hospital

    Omaha, Nebraska, 68114, United States

  • Princess Margaret Cancer Center

    Toronto, Ontario, M5G 2C1, Canada

  • Pusan National University

    Busan, 49241, South Korea

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Seoul National University Hospital

    Seoul, 03080, South Korea

  • Severance Hospital

    Seoul, 03722, South Korea

  • The Cancer and Hematology Centers

    Grand Rapids, Michigan, 49503, United States

  • The Ottawa Hospital Cancer Centre

    Ottawa, Ontario, K1H 8L6, Canada

  • USC/Norris Comprehensive Cancer Center

    Los Angeles, California, 90033, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • Virginia Mason Medical Center

    Seattle, Washington, 98101, United States

Conditions

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