New combo tackles lung cancer brain spread after standard drug fails

NCT ID NCT07361705

First seen Jan 31, 2026 · Last updated May 22, 2026 · Updated 17 times

Summary

This early-stage trial tests whether adding a new drug, zorifertinib, to the existing drug osimertinib is safe and helpful for people with advanced lung cancer that has spread to the brain and spinal cord lining after osimertinib stopped working. About 42 participants will receive the combination to find the best dose and check for side effects. The goal is to control the disease, not cure it.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital Chinese Academy of Medical Sciences

    Beijing, Beijing Municipality, 100021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.