Glow-in-the-dark dye may help surgeons spot hidden prostate cancer cells
NCT ID NCT07725523
First seen Jul 24, 2026 · Last updated Jul 24, 2026
Summary
This trial tests whether a fluorescent dye called zopocianine can make prostate cancer cells glow under near-infrared light during surgery. Men with prostate cancer scheduled for prostatectomy receive a single dose of the dye before surgery. The goal is to see if the dye helps surgeons detect and remove cancerous tissue that might otherwise be missed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a fluorescent dye called zopocianine (OTL78) that targets prostate cancer cells and glows under near-infrared light during surgery
- What this could lead to
- If successful, this approach could help surgeons remove prostate cancer more completely during prostatectomy, potentially reducing the chance of leaving cancerous tissue behind.
- What could go wrong
- This is an early-phase trial with only 36 participants, so results may not apply broadly. The dye may not reliably distinguish all cancerous tissue, and there is a risk of false positives or false negatives.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Indiana University Health North Hospital
Carmel, Indiana, 46032, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Indiana University School of Medicine
Indianapolis, Indiana, 46202, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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