New JAK3 blocker ZL-82 passes first safety check in healthy volunteers

NCT ID NCT06432738

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a new experimental drug, ZL-82, in 41 healthy adults to see if it is safe and how the body processes it. The drug targets a protein involved in immune signaling. Researchers also checked whether ZL-82 affects the heart's electrical activity. The results will help decide safe doses for future studies in patients.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Peking University Medical Shandong Hospital of Traditional Chinese Medicine

    Zibo, Shandong, 255000, China

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