New shot aims to tame stubborn high blood pressure

NCT ID NCT05103332

Completed Disease control Sponsor: Alnylam Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study tested an experimental drug called zilebesiran in adults whose high blood pressure was not well controlled by their current medication. Over 660 participants received either the new drug or a placebo as an add-on to their standard treatment. The main goal was to see if zilebesiran could safely lower blood pressure over six months.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Clinical Trial Site

Mesa, Arizona, 85213, United States
Clinical Trial Site

Tempe, Arizona, 85281, United States
Clinical Trial Site

Tempe, Arizona, 85282, United States
Clinical Trial Site

Bell Gardens, California, 90201, United States
Clinical Trial Site

Canoga Park, California, 91304, United States
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Carlsbad, California, 92008, United States
Clinical Trial Site

Encinitas, California, 92024, United States
Clinical Trial Site

Garden Grove, California, 92844, United States
Clinical Trial Site

Hollywood, California, 91606, United States
Clinical Trial Site

Huntington Beach, California, 92647, United States
Clinical Trial Site

Irvine, California, 92614, United States
Clinical Trial Site

Long Beach, California, 90805, United States
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Los Angeles, California, 90057, United States
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Mission Hills, California, 91345, United States
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Oceanside, California, 92056, United States
Clinical Trial Site

Panorama City, California, 91402, United States
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San Diego, California, 92103, United States
Clinical Trial Site

Santa Clarita, California, 91355, United States
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South Gate, California, 90280, United States
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Tustin, California, 92780, United States
Clinical Trial Site

Upland, California, 91786, United States
Clinical Trial Site

Washington D.C., District of Columbia, 20011, United States
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Clearwater, Florida, 33756, United States
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Coconut Creek, Florida, 33073, United States
Clinical Trial Site

Coral Gables, Florida, 33134, United States
Clinical Trial Site

Hollywood, Florida, 33021, United States
Clinical Trial Site

Hollywood, Florida, 33024, United States
Clinical Trial Site

Inverness, Florida, 34452, United States
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Jacksonville, Florida, 32256, United States
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Miami, Florida, 33032, United States
Clinical Trial Site

Miami, Florida, 33125, United States
Clinical Trial Site

Miami, Florida, 33135, United States
Clinical Trial Site

Miami, Florida, 33144, United States
Clinical Trial Site

Miami, Florida, 33176, United States
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Naples, Florida, 34105, United States
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Orlando, Florida, 32162, United States
Clinical Trial Site

Orlando, Florida, 32801, United States
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Pembroke Pines, Florida, 33027, United States
Clinical Trial Site

Tampa, Florida, 33603, United States
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Winter Haven, Florida, 33880, United States
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Winter Park, Florida, 32789, United States
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Acworth, Georgia, 30101, United States
Clinical Trial Site

Canton, Georgia, 30114, United States
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Columbus, Georgia, 31904, United States
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Savannah, Georgia, 31406, United States
Clinical Trial Site

Louisville, Kentucky, 40202, United States
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New Orleans, Louisiana, 70769, United States
Clinical Trial Site

Southgate, Michigan, 48195, United States
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Jackson, Mississippi, 39209, United States
Clinical Trial Site

Hazelwood, Missouri, 63042, United States
Clinical Trial Site

Jefferson City, Missouri, 65109, United States
Clinical Trial Site

New York, New York, 10036, United States
Clinical Trial Site

Greensboro, North Carolina, 27403, United States
Clinical Trial Site

Greensboro, North Carolina, 27410, United States
Clinical Trial Site

Monroe, North Carolina, 28112, United States
Clinical Trial Site

Norman, Oklahoma, 73072, United States
Clinical Trial Site

Little River, South Carolina, 29566, United States
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Memphis, Tennessee, 38119, United States
Clinical Trial Site

Amarillo, Texas, 79109, United States
Clinical Trial Site

Coppell, Texas, 75019, United States
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Dallas, Texas, 75251, United States
Clinical Trial Site

Houston, Texas, 77074, United States
Clinical Trial Site

Houston, Texas, 77081, United States
Clinical Trial Site

Lake Jackson, Texas, 77566, United States
Clinical Trial Site

Plano, Texas, 75024, United States
Clinical Trial Site

Sherman, Texas, 75092, United States
Clinical Trial Site

Splendora, Texas, 77372, United States
Clinical Trial Site

Stephenville, Texas, 76401, United States
Clinical Trial Site

Tomball, Texas, 77375, United States
Clinical Trial Site

Waco, Texas, 76708, United States
Clinical Trial Site

Burke, Virginia, 22015, United States
Clinical Trial Site

Kenosha, Wisconsin, 53142, United States
Clinical Trial Site

Brampton, Ontario, Canada
Clinical Trial Site

Concord, Ontario, Canada
Clinical Trial Site

London, Ontario, N5W 6A2, Canada
Clinical Trial Site

Toronto, Ontario, Canada
Clinical Trial Site

Winnipeg, Ontario, Canada
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Chicoutimi, Quebec, Canada
Clinical Trial Site

Lévis, Quebec, Canada
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Pointe-Claire, Quebec, Canada
Clinical Trial Site

Québec, Quebec, Canada
Clinical Trial Site

Sherbrooke, Quebec, Canada
Clinical Trial Site

Trois-Rivières, Quebec, Canada
Clinical Trial Site

Québec, Canada
Clinical Trial Site

Tartu, Estonia
Clinical Trial Site

Frankfurt, Germany
Clinical Trial Site

Riga, Latvia
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Kaunas, Lithuania
Clinical Trial Site

Vilnius, Lithuania
Clinical Trial Site

Częstochowa, Poland
Clinical Trial Site

Gdansk, Poland
Clinical Trial Site

Katowice, Poland
Clinical Trial Site

Staszów, Poland
Clinical Trial Site

Warsaw, Poland
Clinical Trial Site

Wroclaw, Poland
Clinical Trial Site

Bellshill, Lanarkshire, ML4 3NJ, United Kingdom
Clinical Trial Site

Carshalton, United Kingdom
Clinical Trial Site

Edinburgh, United Kingdom
Clinical Trial Site

Fowey, United Kingdom
Clinical Trial Site

Glasgow, United Kingdom
Clinical Trial Site

Lancashire Preston, United Kingdom
Clinical Trial Site

Liskeard, United Kingdom
Clinical Trial Site

London, United Kingdom
Clinical Trial Site

Manchester, United Kingdom
Clinical Trial Site

Newquay, United Kingdom
Clinical Trial Site

Plymouth, United Kingdom
Clinical Trial Site

Sheffield, United Kingdom
Clinical Trial Site

Torpoint, United Kingdom
Clinical Trial site

Winston-Salem, North Carolina, 27157, United States
Clinical Trials Site

Beverly Hills, California, 90211, United States

Conditions

Explore the condition pages connected to this study.

HYPERTENSION