New hope for leukemia patients: targeted drug shows promise in major trial

NCT ID NCT07007312

Recruiting now Disease control Sponsor: Kura Oncology, Inc. Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 25 times

Summary

This study tests whether adding an experimental drug called ziftomenib to standard chemotherapy helps people with a specific genetic type of acute myeloid leukemia (AML) live longer or achieve remission. About 1,300 adults with untreated AML and certain gene changes will receive either ziftomenib or a placebo alongside their regular treatment. The goal is to see if the new drug improves survival and remission rates.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Banner MD Anderson Cancer Center
RECRUITING

Gilbert, Arizona, 85234, United States
Baptist Clinical Research Institute
RECRUITING

Memphis, Tennessee, 38120, United States
Cedars-Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Centre Hospitalier Régional et Universitaire de Nancy Hôpitaux de Brabois
RECRUITING

Vandœuvre-lès-Nancy, 54510, France
Centre Hospitalier Universitaire de Nantes
RECRUITING

Nantes, 44000, France
Centre Hospitalier Universitaire de Saint Etienne
RECRUITING

Saint-Priest-en-Jarez, 42270, France
Centre Hospitalier de Béziers
RECRUITING

Béziers, 35400, France
Chonnam National University Hwasun Hospital
RECRUITING

Hwasun, 58128, South Korea
Chungnam National University Daejeon Hospital
RECRUITING

Daejeon, 35015, South Korea
Colorado Blood Cancer Institute
RECRUITING

Denver, Colorado, 80218, United States
Columbia University
RECRUITING

New York, New York, 10032, United States
Dong-A University Hospital
RECRUITING

Busan, 49201, South Korea
Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States
Froedtert & Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Groupe Hospitalier de la Region de Mulhouse et Sud Alsace Hôpital Emile Muller
RECRUITING

Mulhouse, 68100, France
Hartford HealthCare Cancer Institute
RECRUITING

Hartford, Connecticut, 06106, United States
Helios Klinikum Bad Saarow
RECRUITING

Bad Saarow, 15526, Germany
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Y Politecnico La Fe
RECRUITING

Valencia, 46026, Spain
Hospital de Braga, Centro Clínico Académico de Braga
RECRUITING

Braga, 1099-023, Portugal
Icahn School of Medicine at Mount Sinai
RECRUITING

New York, New York, 10003, United States
L'IRCCS Azienda Ospedaliero - Universitaria di Bologna
RECRUITING

Bologna, 40138, Italy
Moffitt Cancer Center & Research Institute
RECRUITING

Tampa, Florida, 33612, United States
Ohio State University
RECRUITING

Columbus, Ohio, 43210, United States
Rutgers Biomedical and Health Sciences
RECRUITING

New Brunswick, New Jersey, 08903, United States
State University of New York at Buffalo
RECRUITING

Buffalo, New York, 14263, United States
Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37203, United States
Texas Oncology - San Antonio Medical Center
RECRUITING

San Antonio, Texas, 78240, United States
Texas Oncology-Austin Midtown
RECRUITING

Austin, Texas, 78705, United States
Texas Oncology-Presbyterian Cancer Center
RECRUITING

Dallas, Texas, 75231, United States
TriStar Centennial Medical Center
RECRUITING

Nashville, Tennessee, 37203, United States
Ulsan University Hospital
RECRUITING

Ulsan, 44033, South Korea
University Hospital Virgen Del Rocio S.L.
RECRUITING

Seville, 41013, Spain
University of California, Fresno
RECRUITING

Clovis, California, 93611, United States
University of California, Irvine
RECRUITING

Orange, California, 92868, United States
University of California, Los Angeles
RECRUITING

Los Angeles, California, 90095, United States
University of California, San Diego
RECRUITING

La Jolla, California, 92093, United States
University of Colorado
RECRUITING

Aurora, Colorado, 80045, United States
University of Kentucky
RECRUITING

Lexington, Kentucky, 40536, United States
University of Miami
RECRUITING

Miami, Florida, 33136, United States
University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of New Mexico
RECRUITING

Albuquerque, New Mexico, 87131, United States
University of North Carolina, Chapel Hill
RECRUITING

Chapel Hill, North Carolina, 27514, United States
University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Texas
RECRUITING

Houston, Texas, 77030, United States
University of Virginia School of Medicine
RECRUITING

Charlottesville, Virginia, 22903, United States
University of Wisconsin
RECRUITING

Madison, Wisconsin, 53792, United States
Virginia Cancer Specialists
RECRUITING

Manassas, Virginia, 20110, United States
WVU Medicine Wheeling Hospital
RECRUITING

Wheeling, West Virginia, 26003, United States
Wayne State University School of Medicine
RECRUITING

Detroit, Michigan, 48201, United States
Weill Cornell Medical Center
RECRUITING

New York, New York, 10065, United States
Willamette Valley Cancer Institute
RECRUITING

Eugene, Oregon, 97401, United States
Yale University School of Medicine
RECRUITING

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

ACUTE MYELOID LEUKEMIA (AML)