New hope for japanese AML patients: experimental drug ziftomenib enters trial

NCT ID NCT07623616

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests an experimental drug called ziftomenib in 6 Japanese adults with a specific type of acute myeloid leukemia (AML) that has returned or not responded to treatment. The drug is taken as a pill once daily. The goal is to see if it can help control the disease and how safe it is.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ziftomenib

What this could lead to

If successful, this could point toward a new treatment option for Japanese patients with a specific type of AML that has come back or not responded to other therapies.

What could go wrong

This is a very small, early-phase study with only 6 participants, so results may not apply broadly. The drug may not work or could cause side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia acute myeloid leukemia with mutated NPM1

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Chiba Aoba Municipal Hospital

    RECRUITING

    Chiba, Japan

  • Dokkyo Medical University Hospital

    RECRUITING

    Tochigi, Japan

  • Gifu Municipal Hospital

    RECRUITING

    Gifu, Japan

  • Hyogo Medical University Hospital

    NOT_YET_RECRUITING

    Hyōgo, Japan

  • Imamura General Hospital

    RECRUITING

    Kagoshima, Japan

  • Jichi Medical University Hospital

    RECRUITING

    Tochigi, Japan

  • Jichi Medical University Saitama Medical Center

    NOT_YET_RECRUITING

    Saitama, Japan

  • Kanagawa Cancer Center

    RECRUITING

    Kanagawa, Japan

  • Kansai Medical University Hospital

    RECRUITING

    Osaka, Japan

  • Keio University Hospital

    NOT_YET_RECRUITING

    Tokyo, Japan

  • Kurashiki Central Hospital

    RECRUITING

    Okayama, Japan

  • Kyoto University Hospital

    NOT_YET_RECRUITING

    Kyoto, Japan

  • Matsumoto National Hospital

    RECRUITING

    Nagano, Japan

  • Mito Medical Center

    RECRUITING

    Ibaraki, Japan

  • Nagasaki University Hospital

    RECRUITING

    Nagasaki, Japan

  • Nippon Medical School Hospital

    NOT_YET_RECRUITING

    Tokyo, Japan

  • Okayama University Hospital

    RECRUITING

    Okayama, Japan

  • Osaka Metropolitan University Hospital

    RECRUITING

    Osaka, Japan

  • Tohoku University Hospital

    RECRUITING

    Miyagi, Japan

  • Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital

    RECRUITING

    Tokyo, Japan