New hope for japanese patients with hard-to-treat blood cancers

NCT ID NCT04172246

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 28 times

Summary

This study tested a drug called zanubrutinib in 55 Japanese patients with certain types of blood cancers (B-cell malignancies) that had come back or stopped responding to prior treatment. The goal was to check the drug's safety, find the right dose, and see how well it shrinks tumors. Participants took the drug by mouth, and researchers monitored side effects and cancer response.

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Contacts and locations

Locations

  • Aiiku Hospital

    Sapporo, Hokkaido, 064-0804, Japan

  • Aomori Prefectural Central Hospital

    Aomori, 030-8553, Japan

  • Chiba Cancer Center

    Chiba, Chiba, 260-8717, Japan

  • Gifu Municipal Hospital

    Gifu, 500-8513, Japan

  • Kanagawa Cancer Center

    Yokohama, Kanagawa, 241-8515, Japan

  • Kobe City Medical Center General Hospital

    KobeShi, Hyōgo, 650-0047, Japan

  • Kurume University Hospital

    KurumeShi, Fukuoka, 830-0011, Japan

  • Matsuyama Red Cross Hospital

    Matsuyama, Ehime, 790 8524, Japan

  • Nagoya University Hospital

    Nagoya, Aichi-ken, 466-8560, Japan

  • National Cancer Center Hospital

    ChuoKu, Tokyo, 104-0045, Japan

  • National Hospital Organization Hokkaido Cancer Center

    Sapporo, Hokkaido, 003-0804, Japan

  • National Hospital Organization Okayama Medical Center

    Okayama, 701-1192, Japan

  • The Japanese Red Cross Nagasaki Genbaku Hospital

    Nagasaki, 852-8511, Japan

  • Toyohashi Municipal Hospital

    Toyohashishi, Aichi-ken, 441-8570, Japan

  • Yokohama Municipal Citizens Hospital

    Yokohama, 221-0855, Japan

Conditions

Explore the condition pages connected to this study.