New drug duo aims to control rare lymphoma without chemotherapy

NCT ID NCT06647732

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining zanubrutinib (a targeted pill) with rituximab (an antibody infusion) can shrink or control MALT lymphoma, a slow-growing cancer of the lymph nodes and organs. About 42 adults with newly diagnosed advanced disease or lymphoma that returned after local treatment will receive the combination. The goal is to see how many patients achieve complete remission and how long the benefit lasts.

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Conditions

The condition(s) this trial relates to.

Lymphoma, B-Cell, Marginal Zone MALT lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sun Yat-sen Universitiy Cancer Center, Sun Yat-Sen University

    RECRUITING

    Guangzhou, Guangdong, 51000, China