New combo aims to deepen remissions in rare blood cancer

NCT ID NCT07259122

First seen Dec 10, 2025 · Last updated May 10, 2026 · Updated 17 times

Summary

This study tests a combination of three drugs (zanubrutinib, a reduced dose of bendamustine, and a CD20 antibody) in 43 people with untreated Waldenström macroglobulinemia, a rare blood cancer. The goal is to see if this approach can achieve a very good partial response or better. After four cycles of the combo, patients continue on zanubrutinib alone for eight months. The study is not yet recruiting.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • China Institute of Hematology and Blood Diseases Hospital ,Chinese Academy of Medical Sciences

    Tianjin, China, 300020, China

  • Institute of Hematology & Blood Diseases Hospital, China

    Tianjin, Tianjin Municipality, 300020, China

Conditions

Explore the condition pages connected to this study.