New yellow fever vaccine trial for kids could boost global protection
NCT ID NCT07103148
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This Phase 3 trial tests a new yellow fever vaccine (vYF) in about 2,440 healthy children aged 9 months to 5 years. Researchers will compare vYF to two licensed vaccines (Stamaril and YF-VAX) to see if it triggers a strong immune response and is safe. Some children will also receive the MMR vaccine at the same time. The study lasts about 3 years, with a booster dose option for some participants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- yellow fever vaccine (vYF)
- What this could lead to
- If successful, this could provide a safe and effective yellow fever vaccine option for young children, potentially improving protection in endemic areas.
- What could go wrong
- This is a large Phase 3 trial, but results may not show vYF is as good as existing vaccines. Also, long-term safety and effectiveness beyond 3 years are not yet known.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Investigational Site Number : 3400001
RECRUITINGSan Pedro Sula, 21104, Honduras
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Investigational Site Number : 3400002
RECRUITINGTegucigalpa, 11101, Honduras
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Investigational Site Number : 3400003
RECRUITINGTegucigalpa, 11101, Honduras
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Investigational Site Number : 3400005
RECRUITINGSan Pedro Sula, Cortes, 21104, Honduras
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Investigational Site Number : 3400007
RECRUITINGTegucigalpa, 11101, Honduras
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Investigational Site Number : 4840005
RECRUITINGEcatepec de Morelos, 55075, Mexico
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Investigational Site Number : 4840007
RECRUITINGTorreón, Coahuila, 27000, Mexico
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Investigational Site Number : 4840009
RECRUITINGChihuahua City, 31000, Mexico
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Investigational Site Number : 4840013
RECRUITINGCuernavaca, Morelos, 62290, Mexico
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Investigational Site Number : 4840015
RECRUITINGTizimín, Yucatán, 97700, Mexico
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Investigational Site Number : 5910001
RECRUITINGPanama City, 10662, Panama
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Investigational Site Number : 5910002
RECRUITINGPanama City, 10662, Panama
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Investigational Site Number : 5910003
RECRUITINGPanama City, 10662, Panama
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