New yellow fever vaccine trial for kids could boost global protection

NCT ID NCT07103148

Recruiting now ⭐️ VACCINE ⭐️ Sponsor: Sanofi Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This Phase 3 trial tests a new yellow fever vaccine (vYF) in about 2,440 healthy children aged 9 months to 5 years. Researchers will compare vYF to two licensed vaccines (Stamaril and YF-VAX) to see if it triggers a strong immune response and is safe. Some children will also receive the MMR vaccine at the same time. The study lasts about 3 years, with a booster dose option for some participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

yellow fever vaccine (vYF)

What this could lead to

If successful, this could provide a safe and effective yellow fever vaccine option for young children, potentially improving protection in endemic areas.

What could go wrong

This is a large Phase 3 trial, but results may not show vYF is as good as existing vaccines. Also, long-term safety and effectiveness beyond 3 years are not yet known.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

yellow fever prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Investigational Site Number : 3400001

    RECRUITING

    San Pedro Sula, 21104, Honduras

  • Investigational Site Number : 3400002

    RECRUITING

    Tegucigalpa, 11101, Honduras

  • Investigational Site Number : 3400003

    RECRUITING

    Tegucigalpa, 11101, Honduras

  • Investigational Site Number : 3400005

    RECRUITING

    San Pedro Sula, Cortes, 21104, Honduras

  • Investigational Site Number : 3400007

    RECRUITING

    Tegucigalpa, 11101, Honduras

  • Investigational Site Number : 4840005

    RECRUITING

    Ecatepec de Morelos, 55075, Mexico

  • Investigational Site Number : 4840007

    RECRUITING

    Torreón, Coahuila, 27000, Mexico

  • Investigational Site Number : 4840009

    RECRUITING

    Chihuahua City, 31000, Mexico

  • Investigational Site Number : 4840013

    RECRUITING

    Cuernavaca, Morelos, 62290, Mexico

  • Investigational Site Number : 4840015

    RECRUITING

    Tizimín, Yucatán, 97700, Mexico

  • Investigational Site Number : 5910001

    RECRUITING

    Panama City, 10662, Panama

  • Investigational Site Number : 5910002

    RECRUITING

    Panama City, 10662, Panama

  • Investigational Site Number : 5910003

    RECRUITING

    Panama City, 10662, Panama