New hope for advanced tumors? first human trial of XTX301 begins

NCT ID NCT05684965

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This study tests a new drug, XTX301, in people with advanced solid tumors that have not responded to standard treatments. The goal is to find a safe dose and see if the drug can shrink tumors. About 358 participants will take part in this early-phase trial across multiple centers.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hackensack University Medical Center

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • HealthPartners Frauenshuh Cancer center

    RECRUITING

    Saint Louis Park, Minnesota, 55426, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Gabrail Pharmacology Phase 1 Research Center

    RECRUITING

    Canton, Ohio, 44718, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Ohio State University Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43221, United States

    Contact Email: •••••@•••••

  • Tranquil Clinical Research

    RECRUITING

    Webster, Texas, 77598, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University Hospital Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact Email: •••••@•••••

  • University of California, Davis Comprehensive Cancer Center

    RECRUITING

    Sacramento, California, 95817, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pittsburgh Medical Center-Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Yale Cancer Center

    RECRUITING

    New Haven, Connecticut, 06510, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.