New hope for duchenne: drug targets missing protein

NCT ID NCT04906460

First seen Oct 31, 2025 · Last updated May 14, 2026 · Updated 28 times

Summary

This study tests a drug called WVE-N531 in people with Duchenne muscular dystrophy (DMD), a genetic condition that causes muscle weakness. The drug aims to help the body produce a protein called dystrophin, which is missing in DMD. About 26 participants will receive the drug through an IV to see if it is safe and can improve muscle function. The study is still recruiting and includes multiple parts to gather more information.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arkansas Children's Hospital

    RECRUITING

    Little Rock, Arkansas, 72202-3500, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Istiklal Hospital/ Clinical Research Unit

    RECRUITING

    Amman, Jordan

    Contact Email: •••••@•••••

    Contact

  • Oxford Children's Hospital, Oxford University Hospitals NHS Foundation Trust

    RECRUITING

    Headington, Oxford, OX3 9DU, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Rare Disease Research LLC

    RECRUITING

    Atlanta, Georgia, 30329, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Specialty Hospital (TSH)/ Advanced Clinical Center

    RECRUITING

    Amman, Jordan

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.