First step toward a treatment for rare lung and liver disease

NCT ID NCT06186492

First seen Mar 23, 2026 · Last updated May 04, 2026 · Updated 8 times

Summary

This early-stage study tested a new drug called WVE-006 in 47 healthy volunteers to see if it is safe and how the body processes it. The goal is to find the right dose for future studies in people with Alpha-1 Antitrypsin Deficiency, a genetic condition that can damage the lungs and liver. Participants received either the drug or a placebo, and researchers monitored for side effects.

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Contacts and locations

Locations

  • Simbec-Orion Clinical Pharmacology,

    Merthyr Tydfil, Wales, CF48 4DR, United Kingdom

Conditions

Explore the condition pages connected to this study.