New hope for rare lung and liver disease: experimental drug WVE-006 enters human testing
NCT ID NCT06405633
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 24 times
Summary
This study tests an experimental drug called WVE-006 in 24 adults with a genetic condition called alpha-1 antitrypsin deficiency (AATD), which can damage the lungs and liver. The goal is to see if the drug is safe and how it moves through the body. Participants receive either a single dose or multiple doses of the drug, and researchers monitor side effects and changes in blood protein levels.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ALPHA 1-ANTITRYPSIN DEFICIENCY are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Cambridge University - Addenbrooke's Hospital
Cambridge, CB2 0QQ, United Kingdom
-
Dalhousie University - Queen Elizabeth II Health Sciences Centre
Halifax, Nova Scotia, B3H 1V7, Canada
-
Inspiration Research Limited
Toronto, Ontario, M5T 3A9, Canada
-
Queen Elizabeth Hospital, University Hospital Birmingham
Birmingham, B15 2GW, United Kingdom
-
Royal Free London NHS Foundation Trust
London, SW8 3RN, United Kingdom
-
St. Vincent's Hospital, Melbourne
Fitzroy, Victoria, 3065, Australia
-
Turku University Hospital
Turku, 20520, Finland
-
Universitaetsklinikum Aachen, AoeR
Aachen, 52074, Germany
-
Waikato Hospital
Hamilton, 3204, New Zealand
Conditions
Explore the condition pages connected to this study.