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Can extra drugs in a wrist block double Pain-Free time after hand surgery?

NCT ID NCT06826690

Symptom relief Sponsor: Mahmoud Rafaat Mohamed Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 02, 2026 · Last updated Sep 03, 2026 · Updated 1 time

Summary

This trial tests whether adding dexamethasone or dexmedetomidine to a standard wrist block with bupivacaine can extend pain relief after hand surgery. About 160 adults having hand surgery will receive one of four ultrasound-guided wrist block combinations. Researchers will measure how long each combination keeps pain away before the first request for additional pain medication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine with or without dexamethasone or dexmedetomidine as additives to an ultrasound-guided wrist block
What this could lead to
If adding dexamethasone or dexmedetomidine to the wrist block works, patients could enjoy longer pain relief after hand surgery without extra strong painkillers.
What could go wrong
This is a single-center trial with 160 participants, so results may not apply to everyone. Adding these drugs could also raise the risk of side effects like nerve damage or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

160 people

The number who actually took part.

Started

Feb 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- Patients more than or equal 18 years old and are ASA 1-3 Exclusion Criteria: * allergy to used medication * pre exist neuropathy * coagulapthy * cognitive impairment * refusal to participate * Failed block and requiring general anesthesia

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hand surgeries

Contacts and locations

Locations

  • Aswan university hospital

    Aswān, Aswan Governorate, Egypt