Can a less invasive surgery prevent ovarian cancer without harming sexual health?

NCT ID NCT02760849

First seen Jan 07, 2026 · Last updated May 21, 2026 · Updated 23 times

Summary

This study looks at two types of surgery to prevent ovarian cancer in women with certain gene mutations (like BRCA). One surgery removes both ovaries and fallopian tubes, while the other removes only the fallopian tubes first and delays ovary removal. The goal is to see which approach better prevents cancer while also protecting sexual function and emotional well-being. About 374 premenopausal women aged 30-50 are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Laura and Isaac Perlmutter Cancer Center at NYU Langone

    New York, New York, 10016, United States

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • Siteman Cancer Center at Washington University

    St Louis, Missouri, 63110, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

  • University of Pennsylvania/Abramson Cancer Center

    Philadelphia, Pennsylvania, 19104, United States

  • University of Washington Medical Center

    Seattle, Washington, 98195, United States

Conditions

Explore the condition pages connected to this study.