Weekly shot could replace daily insulin for diabetes patients

NCT ID NCT06340854

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 28 times

Summary

This study tested a new insulin, icodec, that is taken just once a week, against a standard daily insulin (glargine) in 429 adults with type 2 diabetes. Participants received either the weekly or daily injection for 6 months. The goal was to see if the weekly insulin controls blood sugar as well as the daily one, and to check for side effects. This is a disease management study, not a cure, as patients will need ongoing insulin treatment.

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Contacts and locations

Locations

  • ABS La Roca del Vallés_Endocrinología

    La Roca Del Vallés, 08430, Spain

  • Accellacare Wilmington

    Wilmington, North Carolina, 28401, United States

  • Advanced Clinical Research LLC

    Bayamón, 00959, Puerto Rico

  • Advanced Investigative Medicine, Inc.

    Hawthorne, California, 90250, United States

  • Amarillo Medical Specialists

    Amarillo, Texas, 79124, United States

  • Amrita Institute Of Medical Sciences & Research Centre

    Kochi, Kerala, 682041, India

  • Belgaum Diabetes Centre

    Belagavi, Karnataka, 590001, India

  • Botho ke Bontle Health Services

    Pretoria, Gauteng, 0184, South Africa

  • Centrum Medyczne Pratia Gdynia

    Gdynia, Pomeranian Voivodeship, 81-338, Poland

  • Centrum Medyczne Pratia Katowice

    Katowice, 40-081, Poland

  • Chellaram Diabetes Institute

    Pune, Maharashtra, 411021, India

  • Christian Medical College and Hospital

    Ludhiana, 141008, India

  • Chrysalis Clinical Research

    St. George, Utah, 84790, United States

  • Clinical Trials Research

    Lincoln, California, 95648, United States

  • Cotton-Oneill Diabetes and End

    Topeka, Kansas, 66606-2806, United States

  • Dr A Amod

    Durban, KwaZulu-Natal, 4092, South Africa

  • Dr MB Moosa's Practice

    Durban, KwaZulu-Natal, 4092, South Africa

  • Dr Mahesh Duki Research And Trial Site

    Durban, KwaZulu-Natal, 4339, South Africa

  • Dr Moosa's Rooms

    Lenasia, Gauteng, 1827, South Africa

  • Endo Res Solutions Inc

    Roswell, Georgia, 30076, United States

  • Futata Tetsuhiro Clinic Meinohama_Internal medicine

    Fukuoka-shi, Fukuoka, 819-0006, Japan

  • Gandhi Hospital & Medical college

    Hyderabad, Telangana, 500003, India

  • Government Institute of Medical Sciences

    Noida, Uttar Pradesh, 201310, India

  • Grant Medical Foundation Ruby Hall Clinic

    Pune, Maharashtra, 411001, India

  • H. Clinico Univ. Virgen de la Victoria

    Málaga, 29010, Spain

  • H.U. Quirónsalud Madrid

    Pozuelo de Alarcón, 28223, Spain

  • Heiwadai Hospital_Internal Medicine

    Miyazaki, Miyazaki, 880-0034, Japan

  • Hemant Makan

    Johannesburg, Gauteng, 1827, South Africa

  • Hospital Clinic i Provincial

    Barcelona, 08036, Spain

  • Hospital de Basurto

    Bilbao, Vizcaya, 48013, Spain

  • InnoDiab Forschung GmbH

    Essen, 45136, Germany

  • Institut für Diabetesforschung GmbH Münster - Dr. med. Rose

    Münster, 48145, Germany

  • Institut für Diabetesforschung Osnabrück

    Osnabrück, 49080, Germany

  • International Diabetes Center

    Minneapolis, Minnesota, 55416, United States

  • Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER)

    Puducherry, Tamil Nadu, 605006, India

  • Jefferson City Medical Group, PC

    Jefferson City, Missouri, 65109, United States

  • Lifecare Hospital and Research Centre

    Bangalore, Karnataka, 560092, India

  • MC Berbatov EOOD, Beli Drin

    Yambol, 8600, Bulgaria

  • MHAT Knyaginya Klementina - Sofia EAD

    Sofia, 1233, Bulgaria

  • Malla Reddy Narayana Multispeciality Hospital

    Hyderabad, Telangana, 500055, India

  • Manati Ctr For Clin Research

    Manati, 00674, Puerto Rico

  • Manipal Hospital, Old Airport Road, Bengaluru

    Bengaluru, Karnataka, 560017, India

  • Medical Center Viva Feniks OOD

    Dobrich, 9300, Bulgaria

  • Medical Centre - Clinic Nova EOOD

    Varna, 9000, Bulgaria

  • Medical Institute of Ministry of interior

    Sofia, 1606, Bulgaria

  • MedicalCenter am Clemenshospital - Schwerpunktpraxis für Diabetologie und Ernährungsmedizin

    Münster, 48153, Germany

  • NZOZ Specjalistyczny Osrodek Internistyczno-Diabetologiczny Małgorzata Arciszewska

    Bialystok, Podlaskie Voivodeship, 15-435, Poland

  • NZOZ Vita-Diabetica Malgorzata Buraczyk

    Bialystok, Podlaskie Voivodeship, 15-879, Poland

  • Noritake Clinic

    Ushiku-shi, Ibaraki, 300-1207, Japan

  • Northeast Research Institute of Florida

    Fleming Island, Florida, 32003, United States

  • Oyama East Clinic_Internal Medicine

    Tochigi, 323-0022, Japan

  • Palm Research Center Inc-Vegas

    Las Vegas, Nevada, 89148, United States

  • Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych I Administracji

    Warsaw, 02-507, Poland

  • PharmQuest Life Sciences LLC

    Greensboro, North Carolina, 27408, United States

  • PlanIt Research, PLLC

    Houston, Texas, 77079, United States

  • Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh

    Chandigarh, 160012, India

  • RED-Institut für medizinische Forschung und Fortbildung GmbH

    Oldenburg in Holstein, 23758, Germany

  • Rainier Clin Res Ctr Inc

    Renton, Washington, 98057, United States

  • Scripps Whittier Diabetes Inst

    La Jolla, California, 92037, United States

  • Seth GS Medical College & KEM Hospital

    Mumbai, Maharashtra, 400012, India

  • South Broward Research LLC

    Miramar, Florida, 33027, United States

  • Southern NH Diabetes and Endo_Nashua

    Nashua, New Hampshire, 03060, United States

  • TOTALL Diabetes Hormone Institute

    Indore, Madhya Pradesh, 452010, India

  • Tokyo Medical Univ. Hospital_Diabetes, Metabolism and Endocrinology

    Shinjuku-ku, Tokyo, Tokyo, 160-0023, Japan

  • Trial Management Associates

    Myrtle Beach, South Carolina, 29572, United States

  • Trialmed CRS

    Piotrkow Trybunalski, Łódź Voivodeship, 97-300, Poland

  • UMHAT Aleksandrovska EAD, Clinic of Endocrinology and Metabolic Diseases

    Sofia, 1431, Bulgaria

  • Univ of Nebraska Medical CTR

    Omaha, Nebraska, 68198-3020, United States

  • Uniwersytecki Szpital Kliniczny w Opolu

    Opole, Opole Voivodeship, 45-401, Poland

  • Velocity Clinical Res-Dallas

    Dallas, Texas, 75230, United States

  • Victorium Clinical Research

    Houston, Texas, 77024, United States

  • Zentrum für klinische Studien Allgäu Oberschwaben

    Wangen, 88239, Germany

Conditions

Explore the condition pages connected to this study.