Can a Pre-Surgery drug reveal ovarian Cancer's DNA secrets?
NCT ID NCT02659241
First seen Nov 01, 2025 · Last updated Jun 13, 2026 · Updated 33 times
Summary
This early-phase trial studies how the drug adavosertib affects tumor DNA in 38 patients with advanced ovarian, fallopian tube, or primary peritoneal cancer before they undergo surgery. The goal is to learn how the drug changes cancer cell DNA and proteins, which may help doctors plan more effective treatments in the future. Participants take the drug for up to 28 days before surgery, and researchers compare their tumor samples to those from untreated patients.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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MD Anderson League City
League City, Texas, 77573, United States
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MD Anderson West Houston
Houston, Texas, 77079, United States
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MD Anderson in Sugar Land
Sugar Land, Texas, 77478, United States
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MD Anderson in The Woodlands
Conroe, Texas, 77384, United States
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Memorial Hermann Memorial City Medical Center
Houston, Texas, 77024, United States
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OHSU Knight Cancer Institute
Portland, Oregon, 97239, United States
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The Woman's Hospital of Texas
Houston, Texas, 77054, United States
Conditions
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