Experimental drug tested for rare genetic lung disease
NCT ID NCT05643495
Summary
This study tested whether the drug VX-864 could help people with a specific genetic form of Alpha-1 antitrypsin deficiency. Researchers enrolled 14 participants with the PiZZ genotype to receive the drug for 48 weeks. The trial was terminated early, and researchers measured changes in protein levels in the blood and monitored safety.
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Contacts and locations
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Locations
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Central Florida Pulmonary Group, P.A.
Orlando, Florida, 32803, United States
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Columbia University Irving Medical Center
New York, New York, 10032, United States
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Hannibal Regional Healthcare System
Hannibal, Missouri, 63401, United States
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Inova Fairfax Medical Campus
Falls Church, Virginia, 22042, United States
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King's College Hospital
London, United Kingdom
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Marsico Clinical Research Center at UNC Pulmonary Clinic
Chapel Hill, North Carolina, 27517, United States
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Renovatio Clinical
Houston, Texas, 77380, United States
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Royal College of Surgeons in Ireland Clinical Research Centre, Beaumont Hospital
Beaumont, Ireland
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The University of Iowa Hospitals and Clinics: Adult Pulmonary Clinic
Iowa City, Iowa, 52242, United States
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University Hospital RWTH Aachen
Aachen, Germany
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University of Florida
Gainesville, Florida, 32610, United States
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
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University of Utah Health
Salt Lake City, Utah, 84108, United States
Conditions
Explore the condition pages connected to this study.