New CF drug combo enters first human safety tests
NCT ID NCT06154447
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 21 times
Summary
This early-stage study tests a new investigational drug called VX-828, alone or combined with other CF medicines, in healthy adults and people with cystic fibrosis. The main goal is to check safety and how the drug moves through the body. About 255 participants will take part to see if the combination is well-tolerated.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AdventHealth Medical Group Pulmonology at Orlando Ridgewood
RECRUITINGOrlando, Florida, 32803, United States
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Altasciences Clinical Kansas
COMPLETEDOverland Park, Kansas, 66212, United States
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Billings Clinic, Pediatric Pulmonary Dept.
RECRUITINGBillings, Montana, 59101, United States
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Cook Children's Pulmonology
RECRUITINGFort Worth, Texas, 76104, United States
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Joe DiMaggio Cycstic Fibrosis & Pulmonary Center
RECRUITINGHollywood, Florida, 33021, United States
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Kentucky Children's Hospital
RECRUITINGLexington, Kentucky, 40508, United States
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New York Medical College
RECRUITINGHawthorne, New York, 10532, United States
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ProMedica Toledo Children's Hospital & ProMedica Central Physicians, LLC
RECRUITINGToledo, Ohio, 43606, United States
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University of Minnesota -Pulmonology
RECRUITINGMinneapolis, Minnesota, 55455, United States
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University of Utah Hospital - Pulmonology
RECRUITINGSalt Lake City, Utah, 84132, United States
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Vermont Lung Center
RECRUITINGColchester, Vermont, 05446, United States
Conditions
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