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New hope for CF patients left behind by current treatments

NCT ID NCT05668741

Recruiting now Disease control Sponsor: Vertex Pharmaceuticals Incorporated Source: ClinicalTrials.gov ↗

Summary

This early-stage study is testing a new drug called VX-522 in adults with cystic fibrosis (CF) who have genetic mutations that don't respond to current CFTR modulator therapies. The main goals are to check if the drug is safe and tolerable, and to see if it improves lung function. It's for a specific group of 39 adults with stable CF disease who meet certain health criteria.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough

    RECRUITING

    Penarth, United Kingdom

  • Boston Children's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Centro Ricerche Cliniche di Verona S.r.l.

    RECRUITING

    Verona, Italy

  • Children's Hospital of Pittsburgh - Pulmonology

    RECRUITING

    Pittsburgh, Pennsylvania, 15224, United States

  • Clinical & Translational Science Unit (CTSU) - Pulmonology

    RECRUITING

    Kansas City, Kansas, 66160, United States

  • Hospital Universitari Vall d´Hebron Servicio de Broncoscopia

    RECRUITING

    Barcelona, Spain

  • Hospital Universitario y Politecnico La Fe - Pulmonology

    RECRUITING

    Valencia, Spain

  • Hospital Virgen del Rocio - Pulmonology

    RECRUITING

    Seville, Spain

  • IRCCS Istituto Giannina Gaslini-Ospedale Pediatrico - Pulmonology

    RECRUITING

    Genova, Italy

  • IRCSS Ospedale Pediatrico Bambino Gesu - Pulmonology

    RECRUITING

    Rome, Italy

  • IUCPQ Pavillon Recherche U-1771

    RECRUITING

    Québec, Canada

  • Karolinska University Hospital - Pulmonology

    RECRUITING

    Stockholm, Sweden

  • MGH - MGfC Pediatric Cystic Fibrosis Center

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Medical University of South Carolina - Pulmonology

    RECRUITING

    Charleston, South Carolina, 29425, United States

  • Medicine at East 85th Street

    RECRUITING

    New York, New York, 10028, United States

  • Memorial Health Services on behalf of Long Beach Memorial Medical Center d/b/a Miller Children's Hospital Long Beach

    RECRUITING

    Long Beach, California, 90806, United States

  • National Jewish Health

    RECRUITING

    Denver, Colorado, 80206, United States

  • Nationwide Children's Hospital

    RECRUITING

    Columbus, Ohio, 43205, United States

  • Northwestern Memorial Hospital - Feinberg Pavilion

    RECRUITING

    Chicago, Illinois, 60611, United States

  • PAREXEL International - Baltimore

    COMPLETED

    Baltimore, Maryland, 21225, United States

  • Papworth Hospital NHS Foundation Trust

    COMPLETED

    Cambridge, United Kingdom

  • Presbyterian Hospital - Pulmonology

    RECRUITING

    New York, New York, 10032, United States

  • Queen Elizabeth University Hospital - Pulmonology

    COMPLETED

    Glasgow, United Kingdom

  • Royal Brompton Hospital

    RECRUITING

    London, United Kingdom

  • Ruhrlandklinik

    RECRUITING

    Essen, Germany

  • Shands Hospital - Pulmonology

    RECRUITING

    Gainesville, Florida, 32610, United States

  • St. Louis Children's Hospital - Pulmonology

    COMPLETED

    St Louis, Missouri, 63110, United States

  • Stanford University - Palo Alto - Pulmonology

    RECRUITING

    Palo Alto, California, 94304, United States

  • Texas Children's Hospital - Wallace Tower - Pulmonology

    ACTIVE_NOT_RECRUITING

    Houston, Texas, 77030, United States

  • The Alfred Hospital - Pulmonology

    RECRUITING

    Melbourne, Australia

  • The Johns Hopkins University - Johns Hopkins Hospital - Pulmonology

    ACTIVE_NOT_RECRUITING

    Baltimore, Maryland, 21287, United States

  • UC Health Holmes Hospital

    RECRUITING

    Cincinnati, Ohio, 45220, United States

  • UH Cleveland Medical Center - Pulmonology

    ACTIVE_NOT_RECRUITING

    Cleveland, Ohio, 44106, United States

  • UMCU - Department of Pulmonology and Tuberculosis

    WITHDRAWN

    Utrecht, Netherlands

  • Universitair Ziekenhuis Gent

    RECRUITING

    Ghent, Belgium

  • University Hospital Southampton NHS Fountion - Southampton General Hospital

    RECRUITING

    Southampton, United Kingdom

  • University of Alabama at Birmingham - Child Health Research Unit

    RECRUITING

    Birmingham, Alabama, 35233, United States

  • University of Calgary Medical Clinic of the Foothills Medical Centre

    RECRUITING

    Calgary, Canada

  • University of Minnesota -Pulmonology

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

  • University of Utah Hospital - Pulmonology

    ACTIVE_NOT_RECRUITING

    Salt Lake City, Utah, 84132, United States

  • University of Wisconsin Hospital and Clinics

    RECRUITING

    Madison, Wisconsin, 53792, United States

  • Vanderbilt Interventional Pulmonology

    RECRUITING

    Nashville, Tennessee, 37232, United States

  • Wythenshawe Hospital - OPD

    RECRUITING

    Manchester, United Kingdom

Conditions

Explore the condition pages connected to this study.

CYSTIC FIBROSIS