New hope for cystic fibrosis patients with no other options
NCT ID NCT05668741
First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 35 times
Summary
This study tests a new drug called VX-522 in adults with cystic fibrosis whose genetic mutations do not respond to existing CFTR modulator therapies. The main goals are to check if the drug is safe and tolerable, and to see if it improves lung function. About 26 participants aged 18 and older will take part in this early-phase trial.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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All Wales Adult Cystic Fibrosis Centre, University Hospital Llandough
Penarth, United Kingdom
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Clinical & Translational Science Unit (CTSU) - Pulmonology
Kansas City, Kansas, 66160, United States
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IUCPQ Pavillon Recherche U-1771
Québec, Canada
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Karolinska University Hospital - Pulmonology
Stockholm, Sweden
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MGH - MGfC Pediatric Cystic Fibrosis Center
Boston, Massachusetts, 02114, United States
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Medical University of South Carolina - Pulmonology
Charleston, South Carolina, 29425, United States
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Memorial Health Services on behalf of Long Beach Memorial Medical Center d/b/a Miller Children's Hospital Long Beach
Long Beach, California, 90806, United States
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National Jewish Health
Denver, Colorado, 80206, United States
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PAREXEL International - Baltimore
Baltimore, Maryland, 21225, United States
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Papworth Hospital NHS Foundation Trust
Cambridge, United Kingdom
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Queen Elizabeth University Hospital - Pulmonology
Glasgow, United Kingdom
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Royal Brompton Hospital
London, United Kingdom
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Ruhrlandklinik
Essen, Germany
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St. Louis Children's Hospital - Pulmonology
St Louis, Missouri, 63110, United States
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Stanford University - Palo Alto - Pulmonology
Palo Alto, California, 94304, United States
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The Alfred Hospital - Pulmonology
Melbourne, Australia
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The Johns Hopkins University - Johns Hopkins Hospital - Pulmonology
Baltimore, Maryland, 21287, United States
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UC Health Holmes Hospital
Cincinnati, Ohio, 45220, United States
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Universitair Ziekenhuis Gent
Ghent, Belgium
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University Hospital Southampton NHS Fountion - Southampton General Hospital
Southampton, United Kingdom
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University of Alabama at Birmingham - Child Health Research Unit
Birmingham, Alabama, 35233, United States
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University of Calgary Medical Clinic of the Foothills Medical Centre
Calgary, Canada
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University of Minnesota -Pulmonology
Minneapolis, Minnesota, 55455, United States
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University of Utah Hospital - Pulmonology
Salt Lake City, Utah, 84132, United States
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Wythenshawe Hospital - OPD
Manchester, United Kingdom
Conditions
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