New drug cocktail shows promise for Hard-to-Treat lymphomas

NCT ID NCT05371054

First seen Dec 12, 2025 · Last updated Apr 24, 2026 · Updated 16 times

Summary

This study tested a new combination of three drugs (VIP152, venetoclax, and prednisone) in 8 adults with aggressive blood cancers like diffuse large B-cell lymphoma that had returned or not responded to prior treatments. The goal was to find a safe dose and see if the combination could shrink tumors. Participants took pills at home and received one drug through an IV at the clinic. The study is now complete, and results will help guide future research.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.