Vulvar cancer breakthrough: personalized surgery based on HPV and p53

NCT ID NCT06358469

First seen Nov 18, 2025 · Last updated May 01, 2026 · Updated 16 times

Summary

This study looks at whether the type of early-stage vulvar cancer (based on HPV and p53 status) needs more or less surgery than usual. About 249 adults with stage I-II vulvar squamous cell carcinoma will have their surgery guided by these markers. The goal is to see if this personalized approach reduces cancer recurrence and improves survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Allan Blair Cancer Centre

    RECRUITING

    Regina, Saskatchewan, S4T 7T1, Canada

    Contact

  • Auckland City Hospital

    RECRUITING

    Auckland, 1023, New Zealand

    Contact Phone: •••-•••-••••

  • BCCA - Kelowna

    RECRUITING

    Kelowna, British Columbia, V1Y 5L3, Canada

    Contact Phone: •••-•••-••••

  • BCCA - Vancouver

    RECRUITING

    Vancouver, British Columbia, V5Z 4E6, Canada

    Contact Phone: •••-•••-••••

  • CHUM-Centre Hospitalier de l'Universite de Montreal

    RECRUITING

    Montreal, Quebec, H2X 3E4, Canada

    Contact Phone: •••-•••-••••

  • CIUSSS de l'Estrie - Centre hospitalier

    RECRUITING

    Sherbrooke, Quebec, J1H 5N4, Canada

    Contact Phone: •••-•••-••••

  • Hotel-Dieu de Quebec

    RECRUITING

    Québec, Quebec, G1R 2J6, Canada

    Contact Phone: •••-•••-••••

  • Juravinski Cancer Centre at Hamilton Health Sciences

    RECRUITING

    Hamilton, Ontario, L8V 5C2, Canada

    Contact Phone: •••-•••-••••

  • Odette Cancer Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact Phone: •••-•••-••••

  • University Health Network

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-••••

Conditions

Explore the condition pages connected to this study.