Virus-Immunotherapy combo shows promise against tough cancers

NCT ID NCT03647163

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 22 times

Summary

This study tests a cancer-killing virus (VSV-IFNβ-NIS) combined with an immunotherapy drug (pembrolizumab) in people with advanced solid tumors, including non-small cell lung cancer, neuroendocrine cancer, and kidney cancer. The goal is to find the safest and most effective dose and see if the combination can shrink tumors. About 86 participants will be enrolled, and the study is currently active but not recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cleveland Clinic Taussig Cancer Institute

    Cleveland, Ohio, 44195, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

Conditions

Explore the condition pages connected to this study.