Could stem cell secretions protect hearing during implant surgery?

NCT ID NCT06545175

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests whether a substance called VSF1.01, made from stem cell secretions, can safely reduce trauma to the inner ear during cochlear implant surgery. Eleven adults with severe hearing loss will receive the treatment directly into the cochlea before the implant is placed. The study primarily checks for side effects, and also looks at whether it helps preserve nerve responses and improve speech understanding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

VSF1.01 (a solution enriched with extracellular vesicles from human umbilical cord mesenchymal stem cells)

What this could lead to

If successful, this could lead to a treatment that reduces inner ear damage during cochlear implant surgery, potentially improving hearing outcomes.

What could go wrong

This is an early-phase trial with only 11 participants, so results may not apply to everyone. The treatment is new and its safety and effectiveness are not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hearing loss disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hannover Medical School, Dept. of Otorhinolaryngology

    RECRUITING

    Hanover, 30625, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••