Could this drug help babies with dwarfism avoid risky brain surgery?

NCT ID NCT04554940

First seen Mar 13, 2026 · Last updated May 08, 2026 · Updated 5 times

Summary

This study tests a drug called vosoritide in infants with achondroplasia (a common form of dwarfism) who are at high risk of needing brain surgery due to a narrow skull opening. The main goal is to see if the drug is safe and if it can help the skull opening grow larger, potentially reducing the need for surgery. About 20 babies under 12 months old are participating.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Guy's and St. Thomas NHS Foundation Trust Evelina Children's Hospital

    London, SE1 7EH, United Kingdom

  • Murdoch Children's Research Institute

    Parkville, Victoria, 3052, Australia

  • Sheffield Children's NHS Foundation Trust

    Sheffield, S10 2TH, United Kingdom

Conditions

Explore the condition pages connected to this study.