New heartburn test could replace uncomfortable procedures
NCT ID NCT07437768
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a 4-week course of vonoprazan, a stronger acid blocker, can help identify which patients with persistent heartburn actually have acid reflux. About 100 adults with symptoms that don't improve on standard treatment will take the drug and complete symptom questionnaires. The goal is to see if response to vonoprazan can replace invasive monitoring tests, making diagnosis easier and cheaper.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- vonoprazan (VOCINTI®)
- What this could lead to
- If successful, this could offer a simpler, non-invasive way to diagnose acid reflux in patients who don't respond to standard heartburn drugs, reducing the need for uncomfortable tests.
- What could go wrong
- This is a small, early-stage study with only 100 participants. The results may not apply to everyone, and the test might not clearly distinguish between acid-related and non-acid-related symptoms.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for NERD are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fu Jen Catholic University Hospital
New Taipei City, Taiwan, 24352, Taiwan
More trials for these conditions
Other studies related to the condition(s) this trial covers.