New shot aims to ease diabetic nerve pain in major trial

NCT ID NCT02427464

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 31 times

Summary

This study tested whether an experimental gene therapy called VM202 could safely reduce pain in people with diabetic peripheral neuropathy. Over 500 adults with type 1 or type 2 diabetes received either VM202 injections or a placebo in their legs. The main goal was to see if the treatment lowered average daily pain scores after 90 days compared to placebo.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PAINFUL DIABETIC NEUROPATHY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Arizona Research Center

    Phoenix, Arizona, 85023, United States

  • Associated Neurologists of Southern Connecticut, PC

    Fairfield, Connecticut, 06824, United States

  • Center for Clinical Research

    San Francisco, California, 94115, United States

  • Clinical Research of West Florida

    Tampa, Florida, 33603, United States

  • Clinical Trials, Inc.

    Little Rock, Arkansas, 72205, United States

  • Columbia University Medical Center Department of Neurology

    New York, New York, 10032, United States

  • Compass Research, LLC

    Orlando, Florida, 32806, United States

  • Diablo Clinical Research, Inc.

    Walnut Creek, California, 94598, United States

  • EVMS (Eastern Virginia Medical School)

    Norfolk, Virginia, 23510, United States

  • Innovative Research of West Florida

    Clearwater, Florida, 33756, United States

  • Martin Foot and Ankle

    York, Pennsylvania, 17402, United States

  • Nerve and Muscle Center of Texas

    Houston, Texas, 77030, United States

  • Neurological Research Institute

    Santa Monica, California, 90404, United States

  • Northern California Research

    Sacramento, California, 95821, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Rainier Clinical Research Center, Inc.

    Renton, Washington, 98057, United States

  • Raleigh Neurology Associates, P.A.

    Raleigh, North Carolina, 27607, United States

  • Richard S. Cherlin, MD

    Los Gatos, California, 95032, United States

  • The Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • UF Health College of Med, Jacksonville

    Jacksonville, Florida, 32207, United States

  • University of Florida McKnight Brain Institute

    Gainesville, Florida, 32611, United States

  • University of Kansas Medical Center Research Institute

    Kansas City, Kansas, 66160, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55455, United States

  • University of Utah -Neurology

    Salt Lake City, Utah, 84132, United States

  • Western Washington Medical Group

    Everett, Washington, 98208, United States

Conditions

Explore the condition pages connected to this study.