New drug aims to stop deadly clots without causing bleeding

NCT ID NCT05785819

Summary

This study tested a new drug, VLX-1005, for people suspected of having heparin-induced thrombocytopenia (HIT), a serious reaction to the common blood thinner heparin that causes low platelets and dangerous clots. Participants received the current standard treatment and were randomly assigned to also get either VLX-1005 or a placebo. The main goal was to see if VLX-1005 could help platelets recover faster and reduce the risk of life-threatening clots and bleeding complications.

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Contacts and locations

Locations

  • Carilion Medical Center

    Roanoke, Virginia, 24014, United States

  • Duke University

    Durham, North Carolina, 27710, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • MedStar Washington Hospital Center

    Washington D.C., District of Columbia, 20010, United States

  • Oregon Health and Science University

    Portland, Oregon, 97239, United States

  • Stanford University

    Stanford, California, 94305, United States

  • Thomas Jefferson University

    Philadelphia, Pennsylvania, 19107, United States

  • University of Colorado

    Aurora, Colorado, 80045, United States

  • University of Michigan

    Ann Arbor, Michigan, 48109, United States

  • University of Washington

    Seattle, Washington, 98195, United States

  • Universiy of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Versiti at Froedtert Hospital

    Milwaukee, Wisconsin, 53226, United States

  • Yale University

    New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.